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Chameleons change color by rearranging a lattice of nanocrystals in one of their top layers of skin cells called iridophores. Chameleons can then stretch this layer, broadening the nanocrystalline lattice, thereby causing it to reflect a different wavelength of light.
Chameleons have acrodont teeth meaning they are an extension of the jawbone. They are not set in sockets nor are they replaced.
Pygmy chameleons are sometimes referred to as False Chameleons. This term is actually incorrect and is in reference to anoles, particularly the Cuban False Anole.
The oldest known chameleon fossil is from the extinct species Chamaeleo caroliquarti. It was found in Europe and is 26 million years old.
Some chameleons play dead to avoid predation; this is called thanatosis.
There are currently 202 recognized chameleon species and 85 of them are found on the island of Madagascar.
The word Brookesia is named after the British naturalist Joshua Brookes.
The word Chamaeleo is derived via Latin from the Greek word khamaileon. It roughly translates to ground lion. Khamai means on the ground and leon means lion.
Chameleons have a very poor sense of smell.
The word Rhampholeon is taken from the Latinized Greek “rhamphos leon” meaning crawling lion.

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