I currently have one side striped chameleon. I keep her in a 38 gallon Reptarium, but a 22 gallon would be fine-they are not hugely active and do not need large housing. They like it cooler-she has one 25 watt bulb (or 40W-I need to check) for a basking spot in the low 80's, but she does not use it very much unless it is quite cold in the room. They also like it a bit more humid, so the Reptarium helps with that. She is also very shy, so I do not mess with her much. She will however taunt my Oustalets if I bring them inside when it is cold-she gets right up where they can see her-and of course all they want to do is have her for a snack! They are pretty small chameleons--about the size of a 3 month old Veiled.