I had a mostly blind female panther. Disabled from birth as far as I could tell. She only seemed to be able to vaguely see the difference between light and dark.
Routine was the key. She knew the sound/feel of the cage opening, and knew in the morning that meant water (eye dropper, held to tip of her nose). I tried to keep to nearly the same time of day, every morning. She knew that soon after, when next the cage was opened, it meant food (held with fingers close to her mouth if a cricket roach or similar, placed directly in front of her on a branch if a silkworm or similar). She knew that mid-day usually meant water and food again, and that late afternoon was only water.
She learned her way around the cage easily enough. Had no trouble thermoregulating.
I was careful not to move things much when cleaning the cage. It made thorough cage cleaning very difficult.
Water was the hardest thing to ensure she got enough of, so I often injected extra water into crickets and roaches, and tried to use a lot of butterworms, silkworms, cabbage loopers, and when I could get them hornworms too.
I used a lot of silkworms and butterworms for her, because she seemed just able to detect the different between their pale coloured bodies and the dark branches. I also had a little "shelf" and dark shallow dish in her cage where I would leave silkworms and butterworms and sometimes fresh molted mealworms or fresh molted supers, and she sometimes managed to grab them (she rarley used her tongue, and would miss if she did - so she just would try to get her mouth right on a bug with limited success). It took a long while to "teach" her where this dish was, by constantly coaxing her to eat in that location.
I think her quality of life was satisfactory. but my quality of life was reduced, in terms of the time it took to care for her. It meant no vacations, no sleeping in (unless my partner took care of the morning routine). for me it was worth it, and indeed as I had hatched her and initially kept her alive it was my responsibility to continue to care for her for her entire life.
She stayed fairly small (partly from her not getting sufficient food when she was little before I realized she couldnt see well enough to hunt). She didnt live nearly as long as others.
