It is always scary to go away for a while... but I try to set up most of my cages where everything is on timers... That way your chams can get the proper lighting and misting while you are gone. Water and light are the most important - they (healthy adults) can make it a while with out food.
With that said, I also usually have a friend go and check to make sure all of the systems are working - they don't necessarily have to know anything about chams, they just have to be able to make sure lights and misters are working! If I am gone for more than a weekend I have little labeled deli cups with crickets and piece of potato. Whenever the "caretaker" comes over they can just pop the deli cup top and stick it in the appropriate cham cage - without having to capture crickets and see how many crickets each different cham needs.
All in all, I try to make everything as simple as possible for whoever is looking in on the animals and never leave the chams for more than a day or two without someone stopping in to check on them.
