You have a lot of issues here so get ready to make a lot of changes and spend a lot of money. Your cham looks like it has MBD or is developing MBD so you're going to need to go to a vet. Dr Willems at Aurora Animal Hospital is where you need to go, she is an experienced chameleon doctor and will be able to help you.
Your first issue is that you have 2 chams in one enclosure that is too small for one cham. I assume your "medium" cage is the 18x18x36 which is the bare minimum for a single juvenile cham. You're going to have to get an entire second enclosure, plus a new first enclosure. 2x2x4 minimum so that you can fit a permanent lay bin in your enclosure. Chameleons lay infertile eggs just like chickens do, even without the presence of a Male.
Your next issue is your lighting. Do you even have a UVB light? You mentioned a basking light and a night light, no UVB. Your cham needs a UVB light or it
will die.
http://www.lightyourreptiles.com/24...-arcadia-6-and-6-5k-day-light-bulbs-included/
You will need 2 of these fixtures, one for each enclosure. You also need to get rid of the night light. Chams need complete darkness to sleep, as well as a drop in temp at night just like in the wild. Yes your household temp will be fine, even in Colorado. I'm in Colorado. It's fine.
You said you're gut loading your crickets "with calcium." What does that mean? Are you just using one of those stupid calcium blocks? You need to gut load with fresh vegetables. Leafy greens and fruits. See the attached images for examples.
Your misting schedule needs to be fixed. You need to mist for at least 2 minutes to trigger their drinking and eye cleaning reflexes. You also need to get a hygrometer to track the humidity. You're in Colorado, this should have been your first purchase tbh these are tropical creatures and we have an unbelievably dry climate. Veileds require a lower humidity than other Panthers, but still enough that you're going to have a hard time keeping it up here. I would recommend wrapping 3 sides in a shower curtain to retain the humidity in the enclosure. I'll tag a couple other keepers from CO who are used to dealing with this who may be able to help.
@Rst_Cham @CamoChameleonsHuman
You need to figure out what supplements you are using, it's very important. You will probably just need to get new supplements tbh. You should purchase the Repashy LoD, it's an all in 1 that you can use every feeding. It makes things very easy, fool proof.
If you dont have any live plants then you definitely do not have "plenty of plants." Live plants help provide humidity as well as a more natural environment for your cham. I dont think you would want to live with just a bunch of plastic furniture and neither does your cham. Get a large pothos at least so they can use the vines as pathways to walk the enclosure.
Your basking branch is far to low to be of any use to your cham, you need to raise to to 7-8 inches below your lighting. It's not really important right now because you dont have a UVB light, but it will be when you get one.
What shop did you get these chams from? If they told you they were 100% healthy when you got them then you should be concerned because that means that your husbandry of these animals is causing them to be ill. You need to make these changes, all of them. Theres no wiggle room.
It’s Zoo med Repti calcium withOUT d3. The shop I go to is specifically a reptile shop but I’ll definitely be asking you guys for help when I need it, I was super excited to find this. 
