How old is she and what species? If she's an adult, an dnot gravid/recovering from laying eggs, she WILL be fine on her own as long as she's got water and was well fed. It's a good idea to get someone to check on her, of course.
If that's not possible, you really shouldnt worry. I draw the line at 7 days, personally. But they wil be fine for much longer.
When I was in college, my brother was "Caring" for my chameleons. I came home one weekend to find out that my veileds, two males two females, had not been fed or watered for a month. They were thirsty as heck, and hungry, but not even thin. Their eyes still looked good, too.
If you give them a good feeding the week prior to you leaving (and they're adults, not growing babies!), AND provide them with enough water for at least a few days, they're fine.
Water is the big factor. For veileds, they can go a week or more EASILY, in an emergency. Other species will go for many days without water, bt it's not a great thing to do, you know?
For a week, food isn't a real issue. I just feed them well, throw some insects in a bowl, and leave. I do this at least twice a year.
your chameleon will reward you with not giving a flip that you've been gone a week. Again, unless it's a melleri - they'll make you think they actually care.
