Fluoridated water contains 0.5 to 1.0 ppm fluoride, usually as the sodium salt. Fluoride has a narrow safety range. In mammals, deficiency is associated with dental caries and with osteoporosis in the aged. Fluoride toxicity (fluorosis), due to accumulation from long-term consumption of high levels, is associated with deformed bones and soft, mottled, and irregularly worn teeth. Animals fed diets deficient in protein, calcium, and vitamin C are more susceptible to fluorosis. Water sources containing high levels of fluoride are found in parts of Arkansas, California, South Carolina, and Texas and may be a risk for fluorosis. In reptiles, fluorosis can mimic the signs of metabolic bone disease (MBD)