Reptisafe

Not at all.

I've been using tap water and there has been no negative side affects at all.

I think using water conditioner within reason is good, but tap is always ok.

An easier way would be to get a filter for your sink and then use the filtered water.
 
I would say it depends on your tap water. Mine is really really bad so if I dont use RO water or go buy gallons of clean water, I need to use it. I also let my water sit out for 24 hours to get rid of the chlorine.
 
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