Reproductive issues...

https://static1.squarespace.com/sta...20ab/1573778190228/Van+Dyke+2014+RBP+Ch+5.pdf
"Whether clutch/litter size is ultimately determined at the initiation of vitellogenesis or by selective ovulation/atresia remains unknown, but exogenous FSH has been shown to increase clutch size in several species (Sinervo and Licht 1991; Jones and Swain 2000). The correlations between body condition (or fat body mass) and clutch/size, along with the observation that artificial increases in FSH stimulate increases in clutch size, suggest that hormones that signal resource abundance to the brain, if they exist, act in a dose-dependent manner. This could provide a mechanism for females to adjust clutch/litter size to abundance based on resource availability".
 
According to AI..
“Chameleon Reproduction Overview
Chameleons exhibit diverse reproductive strategies: “…

“Leptin helps manage the internal energy state, providing a signal that informs the physiological "decision" of the reproductive system to become active when conditions (both internal energy and external cues) are optimal.“

Mice…
“Genetically obese ob/ob mice (lacking en- dogenous leptin) are infertile, and treatment of these animals with exogenous leptin stimulates the activity of the reproductive endocrine system and induces fertility in both sexes.”…
https://scispace.com/pdf/leptin-s-a...ice (lacking,the activity of the reproductive
 
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“In birds, leptin has emerged as a significant regulator of ovarian function, influencing reproductive hormone levels, follicular growth, and sexual maturation, particularly in response to nutritional status and energy balance. Chronic leptin injection into prepubertal fasted pullets for 11 weeks decreased ovarian apoptosis and enhanced plasma LH, FSH, and steroid levels, thereby improving follicle growth and advancing sexual maturation”…
https://www.jstage.jst.go.jp/article/jpsa/62/0/62_2025007/_html/-char/en
 
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