Reproductive issues...

https://static1.squarespace.com/sta...20ab/1573778190228/Van+Dyke+2014+RBP+Ch+5.pdf
"Whether clutch/litter size is ultimately determined at the initiation of vitellogenesis or by selective ovulation/atresia remains unknown, but exogenous FSH has been shown to increase clutch size in several species (Sinervo and Licht 1991; Jones and Swain 2000). The correlations between body condition (or fat body mass) and clutch/size, along with the observation that artificial increases in FSH stimulate increases in clutch size, suggest that hormones that signal resource abundance to the brain, if they exist, act in a dose-dependent manner. This could provide a mechanism for females to adjust clutch/litter size to abundance based on resource availability".
 
According to AI..
“Chameleon Reproduction Overview
Chameleons exhibit diverse reproductive strategies: “…

“Leptin helps manage the internal energy state, providing a signal that informs the physiological "decision" of the reproductive system to become active when conditions (both internal energy and external cues) are optimal.“

Mice…
“Genetically obese ob/ob mice (lacking en- dogenous leptin) are infertile, and treatment of these animals with exogenous leptin stimulates the activity of the reproductive endocrine system and induces fertility in both sexes.”…
https://scispace.com/pdf/leptin-s-a...ice (lacking,the activity of the reproductive
 
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