I have a chameleon that has this condition. I have had him for a year and he came to me that way and the previous owner said he was like that for a year and a half before I got him. I took him to the vet when I first got him. There is really nothing they can do for him. It comes and goes but of late has stayed. I have tried different supplements, no supplements, cutting back on supplements, taking certain feeders out of the diet, etc and nothing really works. From what I can see it is not life threating or my cham would have been dead 2 years ago. If you figure something out, please let me know!!!!. My cham is over 4 years old and got it when he was about 1 1/2 yrs old from the way I see it. I read about giving the chameleon Mylanta to get rid of the edema but I really did not want to mess with that. Like I said obviously it is something that is not going to kill them immediately.