I think I would change powders. There are several methods of providing the nutrients your chameleon needs to it...you can use something like Repashy LoD or you can use three powders that will do the same thing. I've used the three powders for years...so I have no experience with the Repashy but many people on here have used it. the Repashy you use daily and the powders you need and their usage is as follows...you need a phos free calcium powder to dust on,the insects just before feeding the, to the chameleon lightly at almost every feeding to help make up for the often poor ratio of calcium to phos found in most feeder insects. You need a phos free calcium/D3 powder to dust lighhtly on the insects twice a month to ensure the chameleon gets some D3 but leaving it time produce the rest from its exposure to the UVB light we provide. D3from supplements can build up in the system which is why we do it this way. D3 produced from the UVB exposure is safe as long as the chameleon can move in and out of the UVB at will. I also use a vitamin powder lightly twice a month that contains a beta carotene prOformed source of vitamin A. PrOformed sources won't build up in the system like prEformed sources will so this leaves it up to you to decide if/when your chameleon needs some prEformed.
So in addition to the dusting you need proper UVB, proper basking and cage temperatures, proper feeding/gutloading of the insects, etc. If you answer the questions in the how to ask for help thread near the top of the health forum we can check to see if you need to make any changes. A couple of photos of your cage and chameleon would help too.
Hope this helps!