How long has he had the white patches? Those may be his natural coloring, but to my eyes they don’t appear to be. Maybe some others can weigh in on that. However, the bumpy scaley spots do have the look of something like a papilloma, which is basically a warty growth. While ugly, it is relatively benign. It can be given to your other chameleons though, so you’ll need to take simple precautions. Things like hand washing in between handling, using separate feeding utensils/dishes, not sharing any items between chams, no mating, etc will be effective in containing it. One of mine has a papilloma and her enclosure is right next to another and taking the basic precautions I’ve mentioned have contained it to just her.
However, those little raised spots could be something else altogether. Could be a fungal or infectious process, cricket bites, injuries of some sort…is best to have your vet take a look and diagnose them.