you can, but I would make sure the water is warm and he probably will not like it cold! Would you??? lol! If you put HOT water in the misting bottle it will spray warm. Just test on youself first. My cham does not mind being sprayed sometimes but only if the water is warm. If the water is cold, then he runs for the hills!!
It's beneficial to get them wet too, although some people might possibly disagree. If they can get water into their eyes it helps them flush out any dirt in them, which is obviously a good thing. And I personally think they enjoy getting their skin wet every once in a while, and it probably doesn't hurt in keeping their skin hydrated.
I do the exact same thing as Carol suggested, I spray them with hot water and it mists out warmish and they usually love it. With cold water they generally run away from it! Also, it's important to note the intensity of the mist. If it's a fine, gentle mist then it's less likely to spook the cham, but if the jet is much stronger they may run from it regardless. In that case, you might want to spray them indirectly.
i mist all my guys with room temp water, i almost always get them wet, but do not spray them directly. As olimpia said they seem to use to water to rinse their eyes and ive seen them open thier mouth to let drops run off their snout into their mouth. some days they run from the water and some days they love it.
they cant always hide from the rain in the wild.
I spray mine quite often while misting the cages. I always use room temperature water from a reverse osmosis system. I use one of the pump type sprayers as this allows you to get a very nice continuous and gentle "raindrop" effect, and start out with just a few "sprinkles" until they realize what is coming and that way they are not shocked or surprised and rarely try to escape the water - they truly seem to enjoy it. However, if they are basking or if I know they have just left the basking area, I do not spray them......the water will be more of a shock if they are extra warm from the basking light, even if you use heated water!
Great answers, thanks everyone! I sprayed my veiled cham with warm water this morning. I made sure the setting was on fine spray. Only did a small amount as he hissed at me so decided to leave him alone. Do you think the hissing sound of the sprayer had anything to do with this?