Over supplementing a chameleon is unfortunately very easy to do. Different species need different amounts of supplements. For a veiled, the recommended schedule for supplements is calcium powder w/o d3 or phosphorous every other day(every feeding for adults who only eat every other day), calcium powder w/ d3 twice a month, and a multivitamin supplement once a month. Fortunately with veileds it is easy to tell if you are over supplementing with calcium because the excess calcium comes out their nostrils. another way people over supplement is by dusting so heavily their crickets look like little ghosts. There should only be a little bit of powder on them, just enough to see a slight powdered look.
Another form of oversupplementing and even undersupplementing for that matter is vitamin A, or beta carotene. If you oversupplement your vitamins this can happen and requires immediate veterinary attention. Some symptoms of vitamin A toxicity are lethargy, eyes closed, and anorexia(not eating). This leads to MBD and toxicity of organs because Vitamin A in conjunction with vitamin D3 cancels it out so they can not absorb the D3. In conjunction, Vitamin A deficiency can also lead to these symptoms but is easier to treat.
Another problem of oversupplementing is vitamin D3 toxicity. High levels of Vitamin D3 and calcium can lead to toxicity of organs and gout.
Another problem is also too much protein in the diet. Some people like to gutload their feeders with cat and dog food. This is a big no no. Cat and dog food is very high in protein and too much given to the chameleon over a period of time will cause gout and kidney failure. Feeders should be gutloaded with fresh fruits and veggies and a specially made dry feeder diet such as cricket crack. This also gives the chameleon essential vitamins and minerals such as vitamin A and calcium/phosphorus.
It is also important to know the nutrition value of your gutload so you do not feed them too much fresh foods with high oxolates. Feeding food high in oxolates cancels out the calcium and can also cause kidney failure. Here is a blog that one of our members made that is very helpful with this aspect:
https://www.chameleonforums.com/blogs/sandrachameleon/nutritional-information/
It is very important to learn exactly how to supplement your species and learn about which supplements to use. Repcal and Herptivite are the recommended supplements to use. Here is another blog by Sandrachameleon that compares different supplement brands:
https://www.chameleonforums.com/blogs/sandrachameleon/174-whats-supplements-brand.html
That's all I have for now, there are probably more ways to oversupplement but I can not think of them at the moment.