Jackson chameleon has grey spots and wont open eyes

That doesn’t sound good at all! If I were you I would set him in the bottom of his cage and see what he does. He may surprise you and just climb up a branch. He may just be so stressed from you holding him that he’s shutting down.
 
I'm not sure how it happened he was fine earlier today he was drinking water and moving around his enclosure, I left for the gym when I found him on the floor like that
 
Please try the vet that Kinyonga posted the link to. Call first thing in the am and tell them it’s an emergency and hopefully they can get you in. keep us posted on how he’s doing!
 
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