I clean around my chameleon...he gives me dirty looks the whole time. I've only handled him twice in the 5 months I've had him, once to show him to my mother in law, once to move him to a new enclosure. He was all "Jurassic Park Dinosaur" both times...him with his little 3 inch long body acting like he could eat everyone in the house...
It was completely hysterical.
There are people here who have ideas on making friends with your chameleon. Me, I don't try. So, if you aren't getting the response you want, maybe search the forums for earlier threads. It's definitely been discussed before.
(note, I have a little Fischers chameleon that was a runt the breeder sold off for less money, he's tiny)