My leopard geckos get grumpy as heck, and they don't have eye caps. I imagine it has to feel weird for them, wearing a second layer around for a brief period of time. Chams or geckos don't usually like to be touched, and then they get stuck for a few days wrapped up in tight old skin that's touching every part of them. I've noticed mine don't want to move around much once they've gotten cloudy.
And yeah, snakes can get dangerous because they are practically blind before a shed. Mine doesn't get aggressive (though some do), but he does think that anything moving is his dinner which makes doing anything near him a game of keep away. Not so much grumpy as clueless! He also hates to move around when he's cloudy.