Previous posts correct...
Male chameleons of many species generally turn brighter colors when handled just as they would in the presence of another male chameleon. This is for intimidation, but if you handle him too often or too long, he will turn darker drab colors just as a losing chameleon in a standoff would. Chameleons with naturally dominant personalities will stay fired up longer. My males have always been the brightest when sleeping, pissed, or courting a female. People often misunderstand bright colors to mean contentness, but have you ever noticed that when chameleons are crammed into one cage in a pet store, they will all be bright beautiful colors? Of course, color changes in females is a whole different story.
Also, as Will suggested, chamelons will often climb up you when you are trying to put them in thier cage because you are taller than the cage. Tree dwelling chameleons like it up high, so elevating the cage will make them feel safer.