I never had a spay female ,Im guessing its like castrate a male on the reproduction 101....I will belive by lowering the temperature in the non spay female cage will slow down her eggs production but NOT completely,humidity should stay within the requirements on the specific female chams needs...like panther...veiled....etc..etc
And I do know it will cost alot to jus spaying a female as far as the vet clinic goes,the best thing to do is try figure out why does a female cham need to be spay in the first place then consult with several chameleon specialist vets and hear what are their opinions then proceed from there,but one thing I DO know that I can tell u is ,if Im the female chams,I will never let myself to get spay,just because I love the babies chamies n pleasure of conceive very very much,and that is "if Im a female cham"