Zoonoses.......
They call things that can be transferred from reptiles to people "zoonoses". And yes, there are several things that can be transferred. Salmonella being the number one thing. Salmonella is a biggie. Children and the elderly can become extremely sick from it. Another thing that a lot of people don't think of is that many parasites that chameleons get can easily be transferred to a dog or cat.
Worms, other nematodes, protozoans and coccidia are all transferred to dogs and cats. That is my biggest worry for people who let their chameleon, or other reptile, sit or walk on surfaces around their house. Invisible cysts or spores that are on the reptiles tail or feet can easily be deposited on surfaces around the house. Some can live for a year on a dry surface. Then a dog or cat sniffs that area because they can smell the reptile on the surface. Then they lick the area around their nose and ingest the cysts/spores.
So........wash your hands every time you handle a reptile. And get a complete check for parasites done before you let your reptile walk or climb on anything in your house.