I suppose for a chameleon that does not eat vegatation it could be attempted. They have irratating sap. I would kind of be careful. The rubber plant (ficus) has a similiar guidline of irratable sap but with the big leaves, it can also be found in the leaves. Leaves are easily punctrude by nails and then would be exposed to the chameleon. I do not know if a croton would be the same.