See by feedback in red bold. Let me know what questions you have. I may have a few additional as well. 
Chameleon Info:
Chameleon - Panther Chameleon , male, and 3 years and 5 months ish, must be around 2 years and 6 months I've had him.
Handling - I generally try take him out as often as I can but he doesn't always come out so he comes out around 2 times a week maybe 2 times in 2 weeks, it really depends on how adventurous he's feeling.
Feeding - I feed him locusts mainly, however I do feed him morioworms (I know they aren't the best and are hard to digest however they are like a treat for him every once in a while often I try to avoid giving him too many and too often), Ive tried him on crickets but he wasn't crazy about them - and to be honest neither was I- I have tried him on silkworms as another treat however it is hard to get my hands on them in any shops. I feed him around 5-8 locusts, moriosworms generally 2 maybe 3. I feed him every 2 days I find this works for him as I do monitor his weight and he seems healthy, he isn't gaining or loosing any weight, I give them sweet potatoes, carrots, cauliflower, lettuce, cabbage, sweet peppers, cucumbers also some fruits like tomatoes, mango, blueberries, grapes, apples, strawberries.
This is all good.
Supplements - I use Calcium-dust by vetark. (I'll attach a picture) and I also use the nutrobal from vetark. Generally I use the Calci-dust almost every feeding, with the nutrobal I use like 1 every 2 weeks, I also sometimes just feed him his food without dusting but mainly I use the calci-dust.
So for your supplements you would use the calci dust at every feeding and then the Nutrobal only 2 times a month say the 1st and the 15th. It is important to use the supplements so that they balance the calcium to phosphorus ratio of the feeder. Now with the nutrobal it has very high levels of A and D3 so only use this 2 times a month. Overdoing it can cause issues as well with fat soluble vitamins like these because they store in the tissues.
Watering - I hand mist the cage often when ever I feel like its too dry. I use a water sprayer on regular timings it goes off every hour for around 20 seconds each time. However the sprayer gets turned off at night when he goes to sleep. I do sometimes see my chameleon drink, honestly recently he's come and almost asked to be sprayed on the mouth for water when I hand spray I didn't know whether to be concerned or not but he closes his mouth when he doesn't want anymore, tbh I think he's just become reliant on me as I saw other people having the same issue.
So this is a sign that he is not getting enough to drink. You need to switch up your watering schedule. They really need a minimum of 2 minutes to fully trigger a drinking response. I would have it mist in the morning when it is cooler and then in the late afternoon running longer misting sessions. During the day the cage needs to dry out from misting. The longer misting sessions will also give him the opportunity to clean his eyes. He may be closing the one due to having something in it. You can also add a dripper to the cage during the day. Take a plastic cup poke a few tiny holes in the bottom. Put ice cubes in it and set on top of the cage. This will melt slowly and drip down onto the plants for him to drink.
Fecal Description - His pee has been white maybe sometimes with slight orange tint to it but overall I'm quite happy about the size and colour of his pee. However every now and then his poo is a but runny, it has good colour and good size, He has never been tested for parasites, I need to but the vets are far away.
Fecal is always a good idea to ensure there is not a parasite issue.
History - I don't think there's any history
Cage Info:
Cage Type - My cage is a wooden cage but has glass doors, It has plenty of ventilation in the back and front, the size is 57.5cmX49cmX91.5cm I'm going to build him a larger one for him as he is outgrowing his cage a bit.
If you rebuild the cage you want to have all lights on top of the cage. Having them inside poses a thermal burn risk.
Lighting - Im using the "Reptile System T8 Zone 2 6% UVI 2.0 15W"
For your UVB are you using a solarmeter to determine the UVI? T8 fixtures do not put out the same UVI level that a T5HO will. So for a Panther your looking for a 3 UVI. A 2 UVI is better than nothing but 3 is considered optimal. I would recommend switching to a T5HO fixture and a 6% or 5.0 linear bulb. You want this fixture to run the width of the enclosure and sit on top of the screen. Then you would have an 8-9 inch distance to the branches directly below it to put the cham in a 3 UVI range. I did use the red lamp "Arcadia 100W, Infrared solar basking E27" This is not our usual one normally it was the "Habistat red night spotlamp150w ES" I have now replaced it with a bulb that is a white/yellow . this originally was what we where planning to use (I've forgotten what brand and type it is but ill try to fund out asap and even find a better one.) we changed to the red lamp since the reptile person recomended when we got him, it seemed okay to trust his opinion, his light turns on at 6:30 am- 6:30 pm, since it gets cold in my house we keep the heat lamp on at a lower temp than in the day. it doesn't emit much light to my eye but of course their eyes are different
Yep no red bulbs at night or during the day.
Temperature - Near the basking light its around 80-85 F (sometimes it may reach 90 on hot days but if it does I make sure to turn it down and get it colder asap.) At night its around 70-74F but now I realise I need to lower that temp at night. We generally have a thermometer in there, but we also have a wire that measures the temp under the heat bulb and controls the heat emitted by the temp its at.
So you really want temps to be able to drop at night down to 60 is perfectly fine for them. If for any reason you were to have to use heat at night you would use a CHE bulb but these have to be on top of the cage. These are high risk for thermal burns. Use a low watt one because they produce a lot of heat. These should also be on a thermostat to control how hot it gets at night. You still want it cool. But if your house gets below 50 then you have to add heat. Too cold is not good either.
Humidity - Humidity generally is varied from 60-85% I mist the cage often and the sprayers that go off also increase the humidity. Normally the thermometer I get also has a humidity meter under it also to monitor both.
So your looking for 50-60% during the day for him. and then at night it can be high but it has to be cool as well or they can develop a respiratory infection.
Plants - Yes I do use live plants I've forgotten specifically which however I do thorough research to check its safe
Placement - Currently its located in my living room. He's ontop a cabinet to allow him a higher placement and is quite happy there as he gets to see the everything,
Location - Im located in the UK.
Current Problem - His left eye facing him/Right eye from his perspective is closed during the day and Im not sure is something is stuck in it or a lack of vitamin A and just wondering how long I should help him at home before a get him to the vet as I don't want to cause stress to him if its a minor issue.
It would not be due to lack of vitamin A. Your nutrobal has high levels of A. Either he has something in the eye or his UVB is not producing as it should be. Lower UVI can cause them to start closing eyes. Could also be a sign of infection but since it is just one eye I am leaning away from this right now. I would increase the misting times so he has an opportunity to clean the eye. I would also look at upgrading the UVB> Unless you have a solarmeter and know exactly what the UVI level is at his back when he basks.