Since you cannot guarantee that;
-Everyone will keep records of it
-That keepers are educated enough to know the differences
-That the records will be passed on as the chameleons are passed to other keepers
-That Wholesalers, who are profit-driven will ensure this
-As always there is a risk of mixing up females, this just complicates it further.
It's jsut one of thsoe things were one person can ruin it for everyone, and so it shouldn't be done at all.
And as said before, or just simply;
-Purebred locales are stunning enough!!!
-There have been documented genetic weakening in mixed offspring.
-Why not strive to breed better pure locales using known liniages, rather than mixing and creating potentially ugly offspring. With cross locales there is an unknown factor, they wont always come out as beautiful as the ones you see from the Kammers. Remember those photos are Holdbacks ("picks of the litter") chosen from likely half a dozen clutches!
-Not speaking strictly about Panthers, but there is a risk of importation of these reptiles being cut off. There may be a possibility that Farm breeding them and captive specimens could help to repopulate the wild. Sure, its a bit wild of a theory, but it's been done with many mammal species and birds.
I'm sure of two things.
One, that there are plenty more reasons why not to do it, than why to.
Two, One of the few if any reasons to, is for
potentially nice offspring.
Potentially.