Now with this 'new to me' Vitamin A information I am leaning toward a deficiency as the cause of my guy's eye problems as well. Could this be possible and not just an eye infection gone wrong?
Yes- after reading some pretty strong anti vit a advice here on the forums by some pretty vocal experts, I tried going vit a free a couple of years ago with a pair of baby panther chameleons. This was in spite of a negative panther egg incubation experience (horrible hatch rate) after switching to herptivite when it first came onto the market years ago. Because others here are using it successfully so I figured I'd give it a try again thinking maybe the egg experience was coincidental.
Within several months, my female showed what I thought was an infection. I tried a good antibiotic eye ointment for a couple weeks with no luck (vet provided- I have vets in my family and others as friends). Finally I decided to go with my gut and stop the ointment and give her a drop of vit a from a gel-cap every couple of days for a few times. The "infection" cleared up after a few doses.
I'm back on reptivite. I see a fair amount of problems here on the forums regularly (eyes, tongue, mbd, crooked casques, chameleon falling) that get posted for help that are probably related to too little a and/or d3.
From 1992 to 1999 I produced quite a few (thousands) of panthers and veileds and occasionally a number of other species. I used rep-cal with d3 each feeding, 1x per week I used reptivite. My father and I necropsied many of my breeders as they passed away during those years. It wasn't the sort where we sent stuff off to the lab, but we had a pretty good look-see around inside most of them (should say my father was a vet with a PHD who worked in a research/teaching setting).
We never found any evidence of too much d3 or vit a in spite of this schedule which would be considered a *lot* by today's standards here on the forums. Of course rep-cal only sticks for a short time and I generally feed enough to last a couple of days in the terraria- so a significant portion of my lizards diet have little to no supplement by the time it is consumed. Still...
Recently I also came across the website of a panther chameleon breeder who had been using reptivite as their only supplement on a schedule of every couple feedings and no other supplement after consulting about the product with zoo-med. They were experiencing great success after at least a few years of this schedule and multi-generations. I've no experience with this schedule myself so I am not endorsing it, but I think it does provide a little more evidence that possibly the worry about d3 and a (this product has both) is sometimes taken a little too far.
My feeling is people worry too much about oversupplementation. I'm not saying do what I did, but there is a happy medium that can be easily and reasonably found through regular occasional use that lies somewhere between anxiety about any vit a or vit d being used on the one hand and using it every meal on the other hand that will get the job done without overdose...
I'm not saying vit a and d free cannot be done- hats off to those who can pull it off without problems- only that it is more difficult and unnecessary.
What I just wrote above is intended for non-montaine, heat loving species. Cool species are a bit more sensitive.
I have been giving my chams Herptivite w/Beta Carotene, which reads: 
