I have used (zero VOC painted) peg-board cages for years. The oldest cage I built more than ten years ago (and its still in great condition and being used). Peg-board sides and back on a wood frame is an EXCELLENT choice. It retains heat and humidity far better than a screen cage, whilst allowing plenty of opportunity for air movement. The sturdiness allows for bowls, plants, branches etc to be afixed easily. Toenails will never be ripped out by climbing (which can happen with mesh/screen). Easy to clean. If you caulk all seams and paint, the peg-board and paint hold up very well to water. I've had an inch of water sitting on the bottom for hours, without penetration.
I use a wide spaced wire top, so that the drippers and lights sit outside the cage. The dripper hoses can be easily put in and moved. The UVB easily pentrates (unlike with screen, which blocks a good portion of the UVB). I used acrylic or plexiglass for the doors, for uninhibited viewing of my animals (and NO they do not paw at the "glass" - they totally understand it is there).
The only drawbacks are: 1 - small bugs could escape through the holes and potentially at the doors if your construction isnt perfect (like mine isnt). Through the top too, if you use a wide mesh like I have. 2 - you have to put some thought into drainage. For me, its easy again as I primarily water with drippers, and collect the unused water in a bowl which I remove and dump. I wipe up spills and excess with a towel, which I then hang dry in the same room (adding humidity to the room) and launder weekly. Easier still would be using a shower pan or tiles and drain hole, as in a bathroom shower, with a bucket under (or a fancier drain pipe connected to the house system). 3 - if you scrub hard, over time (years) the paint can wear, but this just makes for a good reason to change the colour when you repaint.
You can see pictures of my cages here:
https://www.chameleonforums.com/members/sandrachameleon-albums-cage.html
(note - pictures taken shortly after re-doing the cages after a house more, so the plants hadnt grown up like they are now)
Plenty of other people have independantly come up with this same idea. For example:
http://www.chameleonnews.com/02JulCaettaKruger.html