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I have the same concerns. Convenia is shown to last less than 24 hours in many reptiles, sometimes even as few as 6 hours. Unlike in carnivores where it can last up to two weeks. It's not used in reptiles for that reason. And I'd be more worried about fungal or viral based on your picture.Covenia is a long acting antibiotic used in dogs and cats. How it is metabolized in chameleons isn't known but in other reptiles, birds, ruminants and primates it is metabolized quickly so one dose may not be sufficient. And it is an antibiotic so not effective against fungal infections.