Alright as someone that knows a more than just a bit about
different fungi I can say it's a matter of fact that there's no way
you're going to live in a sterile environment.. nor should you.
The fungus that is living in your soil is not a plant.
All fungus belong to
another order of life
The variety of fungi that you're keeping is either living with the plant,
off the plant or breaking down the soil's content itself.
If the plant is alive in well it's very likely that the fungi is beneficial
and even intended to be there to begin with (happy / healthy soil is alive)
If the concern you have is with the spores
they may be totally benign (most likely) and not present a major threat.
IF they were able to able to pose a threat, it would not be the eyes
that would be my concern -it would be the lungs.
The probability that your "puffball" is dangerous is really low.
Even then, Panthers evolved in moist forests where fungi will thrive
- just pick the fruiting bodies for now before they mature.
If you wish to limit the problem... first: limit the water in the soil.
The plant will better survive a dry spell much better than any active soil fungi
Replacing the soil isn't going to do anything but restart the process.
You can also introduce some other competitive fungi
and beneficial bacteria into your soil (always a good move)
I recommend this fertilizer... it contains an array "pro-biotic" critters
that will combat soil Pathogens that can harm your plant/pet.
http://drearth.net/index1.php?page=pro
It's cheaper and easier then getting a new plant.
You also wish to limit your soil's water content and or change
to a less nitrogen rich soil - that will help limit anaerobic growth.
Lastly, improve the soil type and drainage
all these in combination should eliminate future fruitings & worry.
enjoy.