TBH I used them early on.
What I found was, they don't last in the environment we create for our chameleons. They get wet, then warm, lights are shining on them, and they have a tendency to flake. They're perfectly fine to use, but once they flake, that's where things can get dangerous for your chameleon.
Not only can the flakes get in your chameleons eye, who is pretty much guaranteed to rub their head on those branches during sheds, but eventually the wire inside also gets exposed.
For me, they simply do not last. And because they can be dangerous when they break down, I won't use them anymore.
Perfectly fine to use while they are in good shape. But for me, some of them only lasted weeks.
So while they are safe to use, I'd highly recommend swapping them out every so often. Which will be costly.
I personally recommend using wild branches. Just fine nice branches of different sizes that don't have bugs, or anything weird looking on them. Scrub them down with some dish soap, hose them off real well, and let them sun bathe until they dry. I did this and outside of pothos, and the window feeder, they're the only thing in my chameleons enclosure and he's doing great. Just put as many as you can, while not making things too tight for him to maneuver in when he is bigger.
Keep in mind this is just MY experience. I believe a lot of chameleon keepers use Flukers vines just fine. This is just what I personally experienced. And since I am lazy, and deathly afraid to cause harm to my chameleon (lol), I just choose what I feel is the safe route: wild branches that are initially cleaned.