I am a fairly new chameleon owner. After about 3 weeks of owning our cham, my son and I took her to a recommended vet who had years of experience with reptiles, specifically chameleons (30+ minutes from us, but well worth it) for a well check up. They called a couple days before our scheduled appointment and requested we bring a stool sample. From everything I learned (i.e. her coloring, her feeding and drinking patterns, the appearance of her eyes and nostrils, her stool frequency, color, and consistency), she seemed to be healthy. Everything checked out, except her poop. She had 4 different types of parasites: pin worms, round worms, giardia, and coccidia. Giardia is easily contracted by humans without frequent, proper hand hygiene. She was on 3 different antibiotics for 2 weeks and my son and I deep cleaned and sanitized her cage every Sunday. I took her stool in for a recheck after she completed her 2 week course of antibiotics, and she was rid of all but 1 of her parasites. She still had coccidia, which we learned can be very difficult to get rid of. She continued on 1 of the antibiotics for another 2 weeks and we continued deep cleaning and sanitizing her cage every Sunday. When taking her stool in to be rechecked after the last course of antibiotics, she was parasite free! WOO! HOO! My son and I and our cat remained parasite free too (I am a little fanatical about hand washing). We always wash with antibacterial soap prior to handling Cami (so we protect her) and immediately after handling her. Also, before and after handling any of her food sources.
Thinking back, I can even remember commenting on it daily, Cami's poop smelled worse than my 12 year old son's man poops. I felt like I needed a gas mask every night when I would clean up her poop and spot clean her enclosure.
Our vet (and another long-time chameleon owner we know) informed us that parasites are one of the biggest chameleon killers if not treated promptly and properly. Parasites can overwhelm their immune systems.
So, please do not wait. Have a stool analysis done sooner than later. My vet charges $28, but would not have just tested her poop without an initial exam, an additional $48. I don't remember exactly, but when all said in done with initial exam, 1st stool analysis, and 3 antibiotics, my cost was somewhere between $125 - $150. He graciously gave us plenty of overfill on the antibiotics, so we had enough to make it through the second 2 week course (her dose was only 0.07 ml each day of the antibiotic we administered for 4 weeks), but each repeat stool analysis was an additional $28.