Assuming you have the appropriate cage size for your species, I would say that water delivery is key with good drainage. The easier it is to get water to the cham via misting, drip, etc. the less issues you will have. Live plants are a big part of keeping humidity up and can provide good cover for your cham to feel safer so less stress. Multiple sized climbing vines/branches both horizontal and vertical at all levels of the cage allow good for thermoregulation. These are among the most important factors IMO when setting up a new cage. This is assuming you are following general guidelines and have done all the checks on temp, drafts, lighting and practice general common sense on the placement of the cage. JMO