When my guy wouldn't go for 3 or 4 days I would get worried & stick him in the shower for 10-15 mins. If he didn't go while he was in there he would the min I get him back to his cage. Now days I just make sure he showers about 3×'s a week, on top of reg daily mistings of course, and he doesn't have a problem going. I think it depends a lot on hydration. I believe I've read that putting them in a shallow bowl of warm water for a few mins could be helpful. If they will allow you to do so. I would check some older posts though & try to find out some better info before trying that. I dont remember the details & would hate to pass along incorrect info that could be more harmful than good. So look into it first. Good luck!