For the past two days he's been hissing like he's trying to get something out of his throat but he keeps doing it. I don't know what it could be or how to help him if he needs it.
Welcome to the forums. I'm sorry to hear that there might be something wrong with your chameleon. Is there a way you could post a video? That would be helpful. I'll get you a link on how to post a video. https://www.chameleonforums.com/how-post-photos-video-3609/