I keep my Melleri in the same room as my panthers, separate cages of course. As with any new animal you want to be sure that you wash your hands really well before handling or touching anything any of your other animals will touch. If it is a WC animal you'll want to get it checked out for parasites and be SURE you are even more careful than usual, especially for the first 90 days. This is true with any new chameleon though. I believe WC Melleri are known for harboring dangerous parasites and bacteria, more because of their giant size than anything else, but extreme care on your part will keep all of your other animals safe.