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Basking 85 F. He has had them since we got them. No larger, smaller, or different.It almost looks like burns that are starting to blister... but if they haven't gotten any worse..... I would honestly get a skin scraping done. What are your basking temps?
I am no vet, but it looks like a healing injury to me.
You can see a line on his neck behind his casque. Disease/infection doesn't usually have such a sharp delineated line unless the disease process started at the site of an injury.
It almost looks like a healed bite wound--you can see the uspide-down smiley rounded V-shape of a bite wound that connects all the lesions together except for one on the head. Are there any marks on the other side of his head?
If he were mine, I would just watch it and keep photographing it so you have a record of the progress. I wouldn't worry if it stays the same. It might appear to get bigger as he sheds, exposing more of the injury.
If you have other reptiles, I would be very careful with biosecurity if you aren't positive of what you are dealing with.
Keeping the spots clean and dry is important! Before it was completely healed I didn't mess with the shed much as long as it was clean because there's a risk of hurting the very delicate new skin or taking of the scabs. After the injury healed I used to soak my guys and if that didnt bring off the shed I would gently rub the areas with olive or coconut oil, it helped release the stuck shed. The spots need to be monitored pretty closely, if you see any sign of infection they need vet attention ASAP.Should I do anything to help the shed or spots?
You are definitely right, that's one of the differences between the iguanas and chams! I should have mentioned that, I apologize. My iggies loved nothing more than a warm bath to soak and poop in, lol.Don't soak your chameleon, for chameleons use showers, chameleons usually don't do well with soaking and do better with showers with warm water.