Clark: What supplements and what schedule are you using .
I wouldn't rule out the possibility of a Vit A issue here.
I experienced the same issues with the REpCal regime. It corrected after switching to Zoomed Reptivite. The major difference is beta carotene vs. Vit A.
I learned of this issue from conversations with Connie Dorval ( a retired Canadian breeder) and from reading posts by Jim from Chamco.
I did call Rep Cal several times to discuss their products. After several unanswered calls , several unreturned voicemails and several unreturned emails that I sent to discuss the research and reasoning to replace Vit A with beta carotene in their formulation, I gave up.
I have never found any research that has confirmed that Panthers can convert beta carotene to vit A. I have found info to the contrary.
Once I started to use Vit A supplementation , I saw a noticeable change. ADDING VIT A MUST BE DONE RESPONSIBLY as it can be toxic.