i got my first chameleon like five weeks ago and it was like two months old and for the first two-three weeks it liked me handling it but then when it figured out that the cage was its it got really protective and i'v just held it off and on every once and a while and its been more freindly...
i just got a vailed chameleon 3 months and i got a like two foot high one foot wide cage and it likes it. i would say to change to a bigger cage at about 9-10 months old