Left eye closed/Vet Proposed Surgery

Hello CF members. Unfortunately, I have a very big cloud over me this week. My beloved blue bar has fallen ill from what I fear is a fatal disease that he may have acquired from two rescue panthers.

Here's the background.
In October I took in two rescue panthers from two different owners. One from Alabama, and another from a frat house an hour away from me in Louisiana. Both came to me with the exact same symptoms of closing their left eyes and the left eye was more sunken in then the right. They could open it when they needed too but when relaxed would close the left eye only. I thought this was hypovitaminesis a and gave them both carotene and retinal sources of vit. a, but they didn't improve any.

At this point I brought them both into the most qualified vet in my area I could find, dr. Neveraz at the Louisiana state University. He saw both of them and drew a culture from the male. The test came back positive for a gram negative bacteria. He also did an eye examination and flush. Both chams were sent home with ciprofloxacin hydrochloride ophthalmic solution, receiving drops in the left eye three times a day and one drop in the right eye once a day. When the test came back positive the dr. then switched them to amikacin with the same amount of administering regimen. I also rinsed the eye out with saline solution each morning. One week later the female stopped eating and drinking, her body became septic and died. At this point the male showed no improvement so i brought him back into the vet. The vet did another examination and then sent him home with batriyl .1 mls by mouth once a day and metacam anti-inflamatory once a day. I also treated the eye topically with terrmycin.

I then brought the male to another local exotic vet who saw nothing wrong with him and recommended liquid tears. The chameleon saw no improvement and identically died as the female did. They both stopped eating and drinking, and became blind. Even force feeding them didn't save them. I have sent the body of the male to dr. Neverez for him to have a necropsy. The necropsy results indicated nothing out of the ordinary.

Just when I thought all this was behind me I noticed today that my 13 month old panther male's left eye was shut closed for a split second. Additionally, his left eye is more sunken is when compared to his right eye. I am really fearful that I may be experiencing the same symptoms that the other two panthers suffered. I am at my whits in with this and have talked to many breeders who all say they have never seen this condition before and have only seen hypo vit. a.

Today the 13 month old panther is closing his eye regularly. I have contacted both Dr. Naverz and Dr. Alfonso to seek their advice on the situation in an attempt to save him. Dr. Alfonso, being in florida won't accept him as a new cases so my only other option is to see Dr. Naverez at the LSU vet school again. The assistant talked to me on the phone yesterday and said that surgery to remove the eye would be the best solution they are looking at right now. I am very doubtful he would survive the surgery and even if he did I am even more doubtful that what ever disease is causing this wouldn't kill him after the surgery. I will have to make a decision tomorrow wither or not to go with the surgery. What should I do?

Here is some more information about their care.

Female rescue panther
was only provided crickets that were not properly gut-loaded when in care of pervious owner
dusting/supplement schedule was adequate
left eye closed and sunken in
was free ranged in the same room as my other panthers once in my care
body became septic and died. stopped eating/drinking and became blind

Male Rescue panther
was only provided crickets that were not properly gutloaded when in care of pervious owner
dusting schedule was off and was provided multi-vitamin 2-3xs a week
left eye closed and sunken in
was free ranged in the same room as my other panthers once in my care
body became septic and died. stoped eating/drinking and became blind

My male panther I've raised since 3months old
provided silkworms, crickets, hornworms, dubia, superworms all gutloaded well
supplements provided by repashy vit.
free ranged in the same room as rescue panthers
just noticed yesterday that one eye is sunken in more than the other and he had it closed for a second. He slightly squints the eye lid on the left side.
5.0 uv linear reptilgo light changed every 6 months
provided outside time 1-2xs a week
basking spot at 92f

here is the link to the two adoptee/rescue panthers
https://www.chameleonforums.com/new-adoptees-vet-visits-68728/

Chameleon Info:
Your Chameleon - The species, sex, and age of your chameleon. How long has it been in your care?

Male panther, 13-14 months old. Had him since he was 3 months old

Handling - How often do you handle your chameleon?

3-4 times a week.


Feeding - What are you feeding your cham? What amount? What is the schedule? How are you gut-loading your feeders?

Feeding every other day 2-3 worms (silk, hornworm, superworm, and crickets) all gutloaded very well.


Supplements - What brand and type of calcium and vitamin products are you dusting your feeders with and what is the schedule?

Repashy all in one


Watering - What kind of watering technique do you use? How often and how long to you mist? Do you see your chameleon drinking?

Mist king setup. mists 4xs a day. chameleon doesn't drink often, gets most of the fluids from his food

Fecal Description - Briefly note colors and consistency from recent droppings. Has this chameleon ever been tested for parasites?

black and white. everything normal

History - Any previous information about your cham that might be useful to others when trying to help you.

He's been perfectly healthy for the most part. Always ate and drank well. There was once when I was on vacation that he was over-supplemented and was acting 'drunk' for a few days because of the over-supplementation.

Cage Info:
Cage Type - Describe your cage (Glass, Screen, Combo?) What are the dimensions?

Free range area. very large. 4x3x8

Lighting - What brand, model, and types of lighting are you using? What is your daily lighting schedule?

5.0 2ft long repti-glo changed every 6 months
basking spot of 92f



All my chams are on 12 hours on 12 hours off schedule.

Temperature - (cage floor to basking spot)? Lowest overnight temp? How do you measure these temps?

92f basking to 72f during the day
66-68f at night



Humidity - What are your humidity levels? How are you creating and maintaining these levels? What do you use to measure humidity?

30-45%

Plants - Are you using live plants? If so, what kind?

dracaena, pothos

Placement - Where is your cage located? Is it near any fans, air vents, or high traffic areas? At what height is the top of the cage relative to your room floor?


The chameleons have their own room with visual barriers between each other.

Location - Where are you geographically located?

Lafayette, Louisiana
 
Sorry to hear about everything going on but I had to post my response that I am actually going through a very similar situation with my little guy right now.

I am at my wits end and cant even bring myself to create a ask for help post... Hoping you get some good advice here as I will be keeping an eye on this thread...

Good luck
 
Hi Jon, I am so sorry to hear that you are having problems with your little man. If Dr. Alfonso can't help then I would recommend Dr. Doug Mader. He's also here in FL but maybe he will consult with you or even allow you to ship your cham to him. IMHO his best chance it for you to get him to a really good reptile vet. I would definitely get another opinion and not rush into surgery.

Link to Dr. Mader below. He's in the office except Tues. and Thursdays when he works at the Miami Zoo.
http://www.marathonvethospital.com/veterinarians.htm
 
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Thank you Jann. It is really tough to see your chameleon die slowly when you have really provided for them for so long.

I have lost a few lately and know just how hard it is to see them sick. Give Dr. Mader a call tomorrow and see what he can do.
 
Howdy John,

Pure speculation on my part but if your Vet detected the presence of gram-negative bacteria, it may also be the case that it is a type that is highly contagious and resistant to the antibiotics being used and maybe even resistant to any antibiotics :(. As Jann suggested, consulting with Dr. Mader might be just the thing needed since he specializes in the pharmacology of antibiotics in exotic pets (I have his book :)). Maybe he will recognize the situation and be able to suggest another antibiotic. Shipping him to Dr. Mader may be too much stress at this point and push him over the edge :(. If it is an infection, it may actually be systemic and not just local to the eye. As many keepers have experienced, eye closure is as often a symptom of a health problem unrelated to the eye itself. Think of eye closure as the same thing a human does when they wince in pain. For chameleons, first, one eye closes, then days later, the other closes and death is not far behind :(. I also agree that from your description, eye surgery is not the answer.
 
I would definitely get another opinion and not rush into surgery.

I agree. If the bacteria is the problem how would anyone determine that removing the eye would remove the threat? Identifying a a "gram negative bacteria" doesn't tell you all that much as there are many types of them. It doesn't seem likely that it is limited to the eye tissue only, and all the handling during surgery might just spread it. You could end up subjecting your poor cham to surgery with no benefits. Poor little thing, I'm wishing you luck.
 
I am so very upset today. Dr. Madar is too busy to make a paid consult call to my vet. I spoke with Dr. Tom Greek yesterday morning before the vet visit and he was very nice and was willing to make a consult call to my vet. My normal vet isn't on call this week so I got to see the louisiana state university chief zoologist who took a CBC, and a rectal swab to grow a culture from. 'Be' has been sent home with injectable antibiotics every other day and new eye drops. Dr. Tully met with the optimologist and they both looked at his eye. It was perfectly clear just as it was in the other two rescue cases. I was hoping to wake up this morning and see some improvement but he is getting worse. I am waiting to hear back from LSU about the CBC results but I have the feeling the CBC will come back fine just as it did with the other two rescue cases.

My little boy is dying and its killing me to watch him suffer. This is really effecting me much more than I would have every imagined. I am really considering getting out of chameleons.

ceftazidime is the eye drops and
diclofenac sodium is the inject. antiboitics
 
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I am so very sorry to hear this. I know well the helpless feeling of having one of my babies ill and not being able to help. I too know the feeling that I am not a good keeper because my little ones have passed away. I often feel like chameleons are not for me. I have always been the person that does not ever go to funerals.....I always send flowers but now I have had to watch my little ones pass over and over.

If it were me I'll call Dr. Mader back again and again and again. It's Wed. so he's is there now. I would be very persistent for a consult. I feel in your situation he is the best vet for the job. I'll be praying that Be will turn around and it will not be the same thing that the two rescues had.
 
i know how you feel, it sux being so helpless. :( Be persistent with that doctor mader guy, if hes the one who can do something, than dont give up
 
CBC isn't dramatic but does show some sign of an infection. Culture results should be in tomorrow. Have a phone call scheduled with the vet first thing in the morning.
 
Howdy Jon,

I'm glad that you were at least able to get a hold of Dr. Greek. I can imagine how jammed-up Dr. Mader's schedule must get with the level of demand coming from outside of his office :(. Let's hope that the new tests pin down a course of treatment that is effective before it's too late. In any event, I hope that the test results will shed more light on the condition so that we can all learn from it. Many of the treatments we use now were brought to light by chameleon keepers such as yourself who went through this kind of ordeal with their chameleon, spent a bunch of money to get the tests done, bought the drugs needed, and hung-in there to be able to report back to the rest of us whether or not there was success.

Good luck, Dave
 
Still waiting to hear about the culture. Getting the preliminary culture results tomorrow. Giving shots to a chameleon is something else...
 
Hang in there man...I cant imagine the level of frustration and stress this is causing. We are working with a reptile that has had very little research done. Some things will be figured out while other issues will take many cases to find the proper diagnosis and treatment.

I admire the commitment you have to your animal.
 
Culture results came back. He has two bacterial infections one: staphylococcus colaglous negative and the other enthrococcus. Leaving in an hour to drive two hours to go get the new antibiotic to add to his drug list. Vet says the prognosis is not good.

:-( I could not be more sad.
 
I really don't know what to say. I'm just really sorry. The whole thing sucks. I am sending you positive thoughts though. I know you always do your best for your chams.

Deb
 
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